Case of the Week: Perihilar Cholangiocarcinoma/Klatskin Tumor (CT & MRI)
In this radiology lecture, we discuss the CT and MRI appearance of perihilar cholangiocarcinoma.
Key points include:
- Perihilar cholangiocarcinoma (AKA Klatskin tumor) occurs at bifurcation of the hepatic duct.
- Cholangiocarcinoma (CC) is a primary malignant tumor of bile duct epithelium, usually adenocarcinoma.
- CC is the most common primary hepatic malignancy after hepatocellular carcinoma (HCC), and most are extrahepatic (as opposed to intrahepatic).
- Appearance of CC is based on growth pattern: Mass-forming, periductal infiltrating, and intraductal growing.
- Risk factors: Parasite infection, choledochal cyst, primary sclerosing cholangitis, recurrent pyogenic cholangitis, and inflammatory bowel disease (ulcerative colitis).
- Patients are usually 65 or older.
- On CT and MRI, perihilar CC appears as a biliary stricture with shouldering/abrupt tapering.
- If a mass is visible, will typically have rimlike enhancement with gradual centripetal enhancement on delayed images, be T2 bright (but not as homogeneous or as bright as hemangioma), and may have a targetlike appearance on DWI (favors CC over HCC).
Click the YouTube Community tab or follow on social media for bonus teaching material posted throughout the week!
Instagram: https://www.instagram.com/radiologistHQ/
Facebook: https://www.facebook.com/radiologistHeadQuarters/
Twitter: https://twitter.com/radiologistHQ
Podcast: Play in new window | Download
Subscribe: Email