Case of the Week: Testicular Epidermoid Cyst (Ultrasound)

In this radiology lecture, we discuss the ultrasound appearance of testicular epidermoid cyst.

Key points include:

  • Testicular epidermoid cyst is a rare, benign, intratesticular neoplasm.
  • Most common in 2nd-4th decades, typically presents as a painless mass.
  • Lamellated, onion-like, bull’s-eye appearance: Alternating hyperechoic and hypoechoic concentric rings.
  • Appearance secondary to cyst filled with layers of keratin and lined with keratinizing squamous epithelium.
  • Non-vascular and sharply marginated.
  • Nonenhancing on MRI.
  • Important to recognize preoperatively because may be treated with conservative surgery.
  • Management somewhat controversial as originally diagnosed with orchiectomy.
  • Increasingly treated with enucleation if frozen sections of mass are consistent and tumor markers are negative.

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